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Chang et al., 2023)

These PS-80-coated nanoparticles can mimic low-density lipoprotein (LDL) particles to participate in LDL-receptor-mediated transcytosis, a feasible drug delivery approach via the binding between the antibodydrug conjugates and their respective receptors

The TECs of patients with DKD are affected by the inflammatory response, resulting in excessive production of intracellular inflammatory mediators which further activate apoptosis, glycolysis, and apoptosis-related pathways and induce renal tubular injury