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New insights from single-cell and spatial profiling of tumor cells and tumor immune microenvironment

225 LutzP

It's best known for its skin-brightening properties, since it acts as a tyrosinase inhibitor (which, like we mentioned, interferes with and slows the pigment production process, resulting in less pigment and therefore, more even skin tone)

[DOI] [PubMed] [Google Scholar] 113.Yang T.T., Koo M.W

In hypoxic tumor microenvironments, hypoxia inducible factor 1 subunit alpha (HIF1A, also known as HIF1) represses DLAT expression and confers resistance to cuproptosis 176 , supporting the existence of a HIF1A-DLAT-GSH regulatory axis