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Description

As an emerging field of intense investigation, ferroptosis mechanisms and their associated pathways have garnered significant attention

In the SURPASS clinical trial program in type 2 diabetes mellitus (T2D), tirzepatide was associated with unprecedented reductions in HbA1c, clinically significant weight loss and other metabolic benefits, combined with low rates of hypoglycaemia across a wide range of patient characteristics

Continuous oxidative damage to mtDNA has been linked to aging, inflammation, carcinogenesis, and the development of malignancy [47]

Chemokines binding to specific receptors on the target cell membrane help to recruit immune cells into the tumor microenvironment, thereby managing immune surveillance, angiogenesis, invasion and metastasis (96)