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One main reason that thyroid patients get low is due to the low stomach acid we get from either being undiagnosed or underdosed due to the TSH lab test, or undertreated with T4-only products like Synthroid or levothyroxine

NMR analysis of Vitamin B12 conformational dynamics during intrinsic factor binding

And this difference, unfortunately, is consistently forgotten by companies trying to sell you B12 supplements

Thats one fewer source of human error in your experimental setup

While a balanced diet and oral supplements are beneficial, IV therapy offers several advantages: Fast Absorption: Nutrients go directly into the bloodstream, bypassing the digestive system