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A double-blind, randomized phase 2 study comparing various doses (1, 5, 10, 15 mg) of once weekly tirzepatide, dulaglutide (1.5 mg) and placebo, in patients with T2DM, showed tirzepatide was superior on weight loss and glucose-lowering compared to both dulaglutide and placebo [52]

Stacking Semax, PE-22-28, and Selank simultaneously would drive BDNF elevation through three different mechanisms, and there is such a thing as too much BDNF