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In this scenario, molecular histidine instead of histidine residue may introduce additional Cu 2+ /carboxyl and Cu 2+ /amino coordination, which is considered as an alternative in catalytic site optimization 33,34,35

Strain thoroughly to remove grounds

Shan et al, 2005

and MAPKi, mitogen-activated protein kinase inhibitors

Patients are advised to avoid driving or operating machinery immediately after use and take the injection under medical supervision for safe pain management