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Jacobsen DW, Gatautis VJ, Green R, Robinson K, Savon SR, Secic M, Ji J, Otto JM, and Taylor LM Jr (1994)

Furthermore, biocompatibility assessments indicated minimal hemolytic activity (less than 5%) and no remarkable major pathological alterations within 48 h after administration, implying that PEGPDA@PLGA microspheres are safe and effective antimicrobial therapies

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Essentially absent at GH-relevant concentrations

Whether cell demise is mediated via necrosis or apoptosis, it is determined through the relative contribution of the above events (Ankarcrona et al., 1995