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also showed the same trend in knee symptoms and daily activity progression using the mean KOOS score in ten participants with degenerative meniscus tears without osteoarthritis according to Stoller classification after 3 months and 6 months of follow up (i.e., KOOS: 56.6 15.7 baseline, 70.2 16.8 post- 3 months, 72.7 18.5 post- 6 months, p = 0.0007)

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NPAS4 is a neuroprotective protein and acts as a TF, regulating the transcription of a diverse set of genes involved in synaptic plasticity, neurotransmission, and neuronal survival 58

We cannot take a sick passenger on an excursion that represents a potential risk for that passenger and for the integrity of the group (this can be evaluated by the guide at the beginning of the tour)