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PMID 9597130

Given that glutamatergic inputs are able to depolarize cell bodies beyond the threshold for action potential firing via summation of small-amplitude EPSPs 27 , such a circuit appears to be robust enough to support patterned electrical activities

A., Rosenbaum, J

Originally developed in the 1990s as a synthetic analog of tuftsin a naturally occurring immunomodulatory peptide fragment derived from immunoglobulin G Selank was specifically engineered to provide anxiolytic and nootropic effects with enhanced metabolic stability