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This underscores the urgent need for the routine monitoring and global harmonization of residue standards

Notably, phosphorothioates and dithioates are often pro-toxicants, requiring oxidative desulfuration by hepatic cytochrome P450 enzymes to convert into active oxon forms (e.g., parathion paraoxon), which are potent acetylcholinesterase inhibitors

Plant Physiol 69:13481349

However, given the large variety of methods for conjugation the skilled person is able to find a conjugation method that does not or least affects the efficacy or functionality of the entities to be conjugated

Important: Researchers should consult product labeling and facility-specific protocols when establishing storage timelines and handling procedures