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While each of these exogenous sources offers distinct advantages (see section 4.2.1), they all encounter the significant challenge of integrating into highly complex adult neuronal networks, which have been meticulously refined during development and are functioning under the straining conditions imposed by neurodegeneration and/or disease at the time of the intervention

Cationic albumin-conjugated chelating agent as a novel brain drug delivery system in neurodegeneration

Corrects Volume Depletion Fast Rapidly expands blood volume to improve circulation and tissue perfusioneasing headache, dizziness, and weakness sooner than oral fluids

However, the absence of formal clinical trials means long-term safety cannot be guaranteed

Hydrogen sulfide inhibits Ca 2+ -induced mitochondrial permeability transition pore opening in adult and old rat heart