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Description

It usually occurs during the first 6 months of VPA therapy and is commonly but not always preceded by minor elevations in transaminases

Cells were grown to 85%95% confluence before they were placed in a humidified 37 C incubator, and cells from passages 520 were used

Ozturk et al., 2014)

The hydrophobic tail of LCACs can be inserted into the membrane and may trigger the nonspecific activation of signaling pathways in the inner mitochondrial membrane to modulate its function, providing new insights into the unique mechanism of action of acylcarnitines in mitochondrial homeostasis [25]