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The HDAC inhibitor Vorinostat doubles CD8+ T-cell granzyme B expression, elevating tumor killing efficiency by 80% (275)

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Mark the date of reconstitution on the vial

Much of this evidence has recently been reviewed in detail elsewhere [2,3]

Scope of Review This review focuses on the chemical nature of GSNO, its biological activities, the evidence that it is an endogenous mediator of NO action, and implications for therapeutic use