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When RA SFs were compared to control SFs, biotin metabolism, lysine degradation, carnitine synthesis, betaine metabolism, glycine and serine metabolism, spermidine and spermine biosynthesis, threonine and 2-oxobutanoate degradation, methionine metabolism, tryptophan metabolism, and glutathione metabolism emerged as the top enriched metabolite sets (Fig

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Design of Bis-spiropyran Ligands as Dipolar Molecule Receptors and Application to in Vivo Glutathione Fluorescent Probes