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Description

Intranasal delivery of dopamine to the striatum using glycol chitosan/sulfobutylether--cyclodextrin based nanoparticles

An IV delivers 100% of the ingredients directly into the bloodstream, bypassing the gastrointestinal tract, which both slows absorption and diminishes the potency of the ingredients

The distinctive SCAN pattern (SCAN detection is described in the Methods), which alternates with foot, hand, mouth motor regions along the central sulcus, was evident in both patients with PD and HC individuals (Fig