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Clinical and molecular diagnosis of cerebrotendinous xanthomatosis with a review of the mutations in the CYP27A1 gene

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In response, these cells may shift their metabolism toward aerobic glycolysis, generating lactate as an end product, to reduce ROS production by avoiding oxidative phosphorylation, and to regenerate NAD through lactic fermentation (205)

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Neutrophils can produce reactive oxygen species (ROS), leading to oxidative stress and DNA damage, thus contributing to the pathogenesis of SLE (78)

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