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The siRNA used in this study were shown as follows: siVector (negative control), Sense Strand: 5-UUCUCCGAACGUGUCACGUTT-3, Antisense Strand: 3-ACGUGACACGUUCGGAGAATT-5

PMCID PMC12270663

Effects on pro- and anti-inflammatory cytokine profiles in the hippocampus Figure 6dg show that the scopolamine administration significantly increased the TNF-, IL-1, IL-6 (pro-inflammatory cytokines) levels and substantially suppressed the IL-10 (anti-inflammatory cytokine) levels with values of 138.45 2.17 pg/mg protein, 1199 40.93 pg/mg protein, 1475.67 35.10 pg/mg protein and 56.09 1.56 pg/mg protein, respectively, compared to the control group with values of 65.62 2.51 pg/mg protein, 496.67 28.43 pg/mg protein, 624.33 23.59 pg/mg protein and 100.92 2.57 pg/mg protein, respectively

In some embodiments, combinations of cryoprotectants and bulking agents (for example, sucrose/glycine or trehalose/mannitol) may be included to both stabilize antibody compositions during freezing and provide a bulking agent for lyophilization

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