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Others don't get enough B12 from their food, which could require vitamin B12 injections to maintain a healthy level

Msaad S, Yangui I, Bahloul N, Abid N, Koubaa M, Hentati Y, et al

doi: 10.3390/cells11030568 21 MorGCardenasI

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Of note, hemolysis is a fundamental feature of SCD and resulting excess hemin exposure 32 while hypoxia has been shown to induce the expression of fetal hemoglobin 33,34 , and promote the transition from expansion to differentiation during stress erythropoiesis 35