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Lack of B12 can lead to a wide variety of hematologic, neurologic, and psychiatric disorders, may increase the risk of cardiovascular disease (8) , and cause pseudo-thrombotic microangiopathy following gastrectomy (55)

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However, most practice management systems flag this combination for review because combined deficiencies suggest a different underlying process-often D51.8 or D52.8 becomes more appropriate than the specific D51.0 designation

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