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In -thalassemia mice, a modest increase in hepcidin expression limited iron overload, reduced the formation of insoluble membrane-bound globin and ROS, and improved anemia

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A distinctive feature of the WD is the excessive consumption of both ultra-processed and fast-foods, rich in unhealthy components typical of the WD, such as saturated fats and refined carbohydrates, but poor in healthy nutrients, such as vitamins, fibers, and trace elements

J Cell Biol, 2018