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Animal: short diet-induced-obesity mouse studies report changes in weight, fat mass, glucose handling, and liver pathology

Injectable B12 is often preferred because it bypasses the digestive system and delivers the vitamin directly into the body

Annual Review of Nutrition

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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis