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2.1 Pathophysiology of Parkinsons disease 2.1.1 Mechanism of neurodegeneration PD is caused by the progressive degradation of dopaminergic nerve cells in the substantia nigra, a part of the brain that is essential for controlling movement (31)

WangYWangCZhuYChenKYuYLiRet al

3.3 Parkinsons disease PD is a neurodegenerative disorder that typically presents later in life with generalized bradykinesia and another symptom of resting tremor or rigidity

ACS Cent Sci

Lipid peroxidation is trigger by the uptaking of hydrogen atoms located between two carbon-carbon double bonds in the lipid bilayer, resulting in the formation of a phospholipid radical at the center of the carbon chain