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Similar to other chronic diseases, if the treatment for the disease of obesity is stopped, weight regain will likely occur and the health benefits will be diminished [14]

[PubMed: 23736363] 79

GLP-1 medications are metabolized through proteolytic degradation, not through the liver's cytochrome P450 enzyme system

[3] This matters enormously for interpretation: a result obtained with CagriSema describes cagrilintide plus a potent GLP-1 analog, and cannot be read as the effect of cagrilintide by itself