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As a potent damage-associated molecular pattern, the released mtDNA can further amplify the inflammatory signal and serve as a structural component of neutrophil extracellular traps (NETs), thus creating a self-amplifying loop of netosis (116, 117)

Diaz Vivancos P, Dong Y, Ziegler K, Markovic J, Pallard FV, Pellny TK, Verrier PJ, Foyer CH (2010b) Recruitment of glutathione into the nucleus during cell proliferation adjusts whole-cell redox homeostasis in Arabidopsis thaliana and lowers the oxidative defence shield