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Presence of GST in cells 3.2.1

10.1038/s43018-021-00299-1 67

Methotrexate reduces the expression of ROS, CD177, and CD11b in circulating neutrophils of patients with RA, which may be one of the mechanisms underlying its treatment of RA (96)

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In March 2011, the FDA placed the trial on clinical hold due to GMP compliance issues at the contract manufacturer not safety concerns with RGN-352 itself