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10.1523/jneurosci.0476-15.2015 25 De BundelD.SmoldersI.VanderheydenP.MichotteY

The therapeutic concentration for the antipyretic effect of acetaminophen is between 10 and 20 micrograms/mL (66 to 132 micromoles/L), but therapeutic concentrations for analgesia are not established

DOI: 10.1007/s40279-018-1015-0

In the lungs, the loss of A1ATs antiprotease function against NE, caused by a significant reduction in A1AT serum levels, results in the destruction of emphysematous lung tissue