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Functioning as a potent exercise mimetic, this small-molecule compound enhances mitochondrial function, fatty acid oxidation, and oxidative muscle fiber composition, thereby improving exercise endurance, cardiac metabolic efficiency, and systemic energy expenditure without increasing food intake 1-4

Crucially, parietal cells in the stomach lining produce a protein called intrinsic factor , which binds to B12 and enables its absorption in the terminal ileum

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Retatrutide is only available through approved clinical trials

Additionally, it acts as a potent antioxidant, combating oxidative stress through the activation of SIRTUIN genes, responsible for producing antioxidants