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The ecological imbalance of intestinal flora, alterations of intestinal cell permeability, liver injury, endoplasmic reticulum stress, abnormal activation of cellular signaling pathway, as well as dietary and genetic factors of patients, have all been implicated in the occurrence of NAFLD (Williams et al.,

Ferroptosis has been implicated in the occurrence and treatment response of various types of cancer, and targeting ferroptosis has emerged as a promising strategy for cancer therapy

This could be due to ga enetic disorder, inadequate intake, diarrhoea, liver or kidney disease, and use of certain medications

Albert GC, Cook CM, Prato FS, Thomas AW

Proton pump inhibitor use: systematic review of global trends and practices