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Abstract Neurodegeneration is among the most critical challenges that involve modern societies and annually influences millions of patients worldwide

Since CAIs are derived from sulfa drugs they can cause an allergic reaction in individuals with sulfa allergies though the level of cross- reactivity is low

These observations in RNA-seq data were further validated by qRT-PCR for selected Wnt/-catenin pathway-related genes including AMER3 , NRARP , CCND1 , LRG1 , and LEF1 in hDP cells exposed with various doses of NTAPP (3.6 kV, 4.2 kV, and 5.0 kV) (Fig