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Therefore, intraperitoneal administration is preferred over the oral route to avoid the potential degradation of biological agents in in vivo animal experiments (127)

Diet-derived ceramides species might target and disrupt mitochondria function leading to defective energy balance and neurodegeneration

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Moreover, as the presence of bioactive molecules as dietary fibers and phenolic acids in wheat, are also implicated in the health of intestinal microbiota by stimulation of the good gut flora development and as well, in the generation of anti-inflammatory SCFA production (44)

16 , ii28ii39 (2023)