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The observation in RCC aligns with our findings showing that HIF2 KO NSCLC cells are dependent on -KG synthesis, which is facilitated by PHGDH and phosphoserine aminotransferase 1 (PSAT1) reactions, and consequently indicates that these cells are specifically sensitive to PHGDH inhibitors rather than to downstream targeting of SHMT by sertraline

2015, December pp.1 doi:10.1016/j.tria.2015.10.004 Loukas M, Du Plessis M, Louis RG Jr, Tubbs RS, Wartmann CT, Apaydin N (2015).The subdiaphragmatic part of the phrenic nerve morphometry and connections to the autonomic ganglia

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Multiple instances of ancient balancing selection shared between humans and chimpanzees

Ali A, Esmaeil A, Behbehani R (2024) Mitochondrial chronic progressive external ophthalmoplegia