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I am unsure the reasoning of the timeframe recommendation

Postsynaptic glutamate acts on N-Methyl-D-aspartic acid receptors (NMDAR), which opens a non-selective cation channel on neurons to permit calcium or sodium ion influx [131]

Zelante T, Iannitti RG, Cunha C, De Luca A, Giovannini G, Pieraccini G, et al

Dilutional hyponatremia may occur in edematous patients in hot weather

29: Takeda secured another indication for its immunoglobulin therapy, GAMMAGARD LIQUID, which, according to the company, is the only intravenous IG (IVIG) therapy for the treatment of multiple neuromuscular disorder indications in the U.S