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They are often used in clinical settings for quick results, particularly for skin lightening

Gasperl A, Balogh E, Boldizsr , Kemeter N, Pirklbauer R, Mstl S, Kalapos B, Szalai G, Mller M, Zellnig G, Kocsy G (2021) Comparison of light condition-dependent differences in the accumulation and subcellular localization of glutathione in Arabidopsis and wheat

Overall, although acrolein possesses the highest reactivity, its overall intracellular abundance is lower than that of MDA and 4-HNE (Schaur et al., 2015)