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its a marker of it

Sigalos, John T, and Alexander W Pastuszak

In rodent and cell work, NNMT knockdown or inhibition has been described as protecting against diet-induced weight gain and improving metabolic measures without reducing food intake [5] [6]

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Dynamic changes in metabolites of the kynurenine pathway in Alzheimers disease, Parkinsons disease, and Huntingtons disease: a systematic Review and meta-analysis