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Asterisks indicate neutral loss of phosphoric acid (H 3 PO 4 , 97.98 Da), which is commonly observed for phosphoserine- and phosphothreonine-containing peptides upon HCD fragmentation

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The initial treatment regimen for patients without neurological involvement typically consists of hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance injections every two to three months for life

Abbreviations AIH: Alcohol-induced hyperlipidemia CM: Cordyceps militaris CM: Cordycepin-rich CM GSH: Glutathione HDL: High-density lipoprotein OS: Oxidative stress PJ: Paecilomyces japonica SD: SpragueDawley SM: Silymarin TBARS: Thiobarbituric acid-reactive substances TC: Total cholesterol TG: Triglyceride References AlHajri L, AlHadhrami A, AlMheiri S, AlMutawa Y, AlHashimi Z (2017) The efficacy of evolocumab in the management of hyperlipidemia: a systematic review

Lipoxin A4 protects against spinal cord injury via regulating Akt/nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 signaling