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In a casecontrol study, exenatide treatment over a 12month period led to a 15% improvement in UPDRS scores in earlystage PD patients, alongside a reduction in CSF neuroinflammatory markers [256]

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Primary kidney cells and IMR90 cells were treated with DMF, a potent inducer of succination-dependent oxidative stress and their proliferation was assessed

Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring

By performing co-culture experiments between wild-type or UBE2I KD cancer cells and CCA-derived cancer-associated fibroblasts (CAFs), human endothelial cells or monocytes, we have unveiled the impact of SUMOylation in the crosstalk between CCA cells and the TME