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Effect of selenium status on thyroid disease Selenium deficiency has been associated with a number of adverse thyroid conditions, including hypothyroidism, subclinical hypothyroidism, enlarged thyroid ( Reference Derumeaux, Valeix and Castetbon 74 Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 ) , thyroid cancer ( Reference Schmutzler, Mentrup and Schomburg 67 , Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 Reference Lin, Kuo and Chiang 79 ) and AITD, including HT ( Reference Wu, Rayman and Lv 75 , Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 ) and GD ( Reference Rayman, Duntas, Luster, Duntas and Wartofsky 77 , Reference Bulow Pedersen, Knudsen and Carle 80 )

The diversity of proposed effects is vast, and so is the quality of the evidence

Clinical evaluation of Guilu Erxian Jiao in treating perimenopausal syndrome

Ferroptosis, a regulated form of cell death, has been identified as a key mechanism of cardiomyocyte loss in models of DOX-induced cardiotoxicity

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