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Environ Heal Perspect 110(Supp (1)):103112 Kode A, Yang S-R, Rahman I (2006) Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells

Wikipedia Insulin-like Growth Factor 1 (IGF-1) Comprehensive overview of IGF-1 biology, receptor interaction, and cellular signalling

Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

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In high amounts, that extracellular NAD can act as a danger signal, prompting your immune system to respond as if your cells were damaged