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We also found that BAY-850 treatment significantly inhibited lung metastasis of BRAF mutant and NRAS mutant melanoma tumors in mice as compared to vehicle treatment (Fig

Plant Soil Environ

doi: 10.3389/fendo.2022.904312 134 XieYLiangBMengZGuoRLiuCYuanYet al

[DOI] [Google Scholar] Tohl D

Blocking excessive activation of this factor is a key target for effectively inhibiting the activation of the contact system, and the use of novel inhibitory antibodies to neutralize FXIIa has been shown to reduce the inflammatory response in animal models of ECMO, as well as thrombosis prevention (52, 53)