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The protein level of significantly increased p16 was confirmed in keloid lesions and fibroblasts based on western blot analysis ( p = 0.0007, p = 0.03

The upregulation of GPX6 expression found in these two studies suggests that its upregulation may have some antioxidant effects

doi: 10.1136/bmj.n71, 81 PalaszE.NiewiadomskiW.GasiorowskaA.WysockaA.StepniewskaA.NiewiadomskaG

Some studies have shown that GSTP1 methylation can serve as a diagnostic tool for HCC with a sensitivity of approximately 50%75% and a specificity of 70%91% ( APC or SOCS (Liu et al., 2015), it can be used for early cancer detection in individuals who are genetically predisposed or exposed to carcinogens (Schnekenburger et al., 2014)

Both are unapproved research chemicals presented here for research and educational purposes only