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Taken together, this study provides immunogenicity assessment which is closely implicated with toxicokinetic study of GX-G3 in 4-week repeated administrated toxicological studies

77,174,175 Of note, GFAP expressed by reactive astrocytes following TBI, or released by damaged or dead astrocytes, can be also detected in the blood and spinal fluid, and the levels of GFAP in these fluids can reflect the severity of trauma and can be used as a diagnostic clinical tool

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Shailesh S., Sahoo P.K

Some compounds may not be well absorbed when taken orally, or they may be rapidly metabolized and cleared before having a meaningful effect