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Melatonin accelerates the phase shift if given at the appropriate time prior to bedtime at destination, and the benefits of melatonin administration in the alleviation of jet lag seems to be greater with larger numbers of time zones (105)

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As a competitive endogenous RNAs (ceRNA), lncRNA HIX003209 exaggerates inflammation through sponging miR-6089 via TLR-4/NF-B pathway in RA macrophages (262)