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Figure 4 Figure 5 Figure 6 Figure 7 Discussion Our results showed that GSH and SA may induce partially overlapping signaling pathways in tobacco to confer resistance to TMV

doi:10.3389/fnmol.2023.1069965 162

The passage of GSH through plasma membrane is regulated by a switch in the open/closed configuration of the transporters, and occurs according to gradient, being in fact uni-directional (i.e., export rather than import) because intracellular levels are much higher than those of body fluids

In parallel, we observed that addition of GSH-OEt to unmodified U937 cells exposed to TNF- led to inhibition of NF- B activation by I B stabilisation (Figure 4C and D), thus mimicking the effect of hGH