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The resulting gut dysbiosis is characterized by a loss of beneficial microbes ( Lactobacillus , Bifidobacterium ) and an expansion of pro-inflammatory pathobionts ( Escherichia-Shigella , Enterococcus ), which further fuels the inflammatory cycle ( F.n on the gut community is not limited to UC but also extends to CD, where specific populations like polymorphum are enriched, an effect more pronounced in male hosts ( The pathogenic role of F.n is even more pronounced in CRC, where it functions as a bona fide oncomicrobe

By integrating CT/magnetic resonance (MR) dual-modality imaging, photothermal/photodynamic responsiveness, drug-loading capability, and effective embolization, these microspheres achieve precise image-guided and laser-enhanced chemoembolization

The exquisite immune specificity for beta cells suggests that such cells may already harbour molecular signatures of vulnerability, which may act not only as initiators or conduits for the early immune response but also as amplifiers of ongoing beta cell-directed immune destruction (Kracht et al

Aksu I, Ates M, Baykara B, Kiray M, Sisman AR, Buyuk E, et al

RNA was precipitated with isopropanol and collected by centrifugation at 12,000 g for 15 min at 4 C