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Additionally, the gut microbiota generates small molecule metabolites like indole and its derivatives, which possess anti-inflammatory and antioxidant properties and can protect the BBB from damage (Feng et al., 2023)

Figure 2 Continue Learning with UWorld Get the full Glucose-6-Phosphate Dehydrogenase Deficiency article plus rich visuals, real-world cases, and in-depth insights from medical experts, all available through the UWorld Medical Library.

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Pharmacological inhibition of GLS via CB-839 or BPTES amplifies PCa cell sensitivity to metformin ( 4.3.7 Limitations of drugs targeting ammonium metabolism Although systematic investigations into the adverse effects of ammonium metabolism-targeting agents in prostate cancer remain limited, their toxicological profiles have been relatively well characterized in other solid tumors, such as breast, pancreatic, and gastrointestinal cancers (211, 222, 238)

A review of its pharmacology, and therapeutic potential in late-onset complications of diabetes mellitus