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Our microarray analysis revealed that the expression of Fgf21 had been altered in WT but not Chrebp -/- hepatocytes after fructose feeding, prompting us to further explore the stimulation of the ChREBP-FGF21 axis and its role in the protection against APAP-induced toxicity

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Evaluation of the effect of taurine in dogs that are naturally RAAS activated and not receiving RAAS inhibiting medications was a strength of this study