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Immunostimulatory plant polysaccharides impede cancer progression and metastasis by avoiding off-target effects

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injured tubules activate fibroblasts or undergo EMT to exacerbate RF, further reducing glomerular filtration rate ( 3.4.3 Targeting ferroptosis to ameliorate RF Ferroptosis is now recognized as a pivotal regulated necrotic pathway in AKI (196), and recurrent AKI drives maladaptive repairmarked by tubular atrophy, fibroblast activation, and excessive ECM depositionculminating in CKD and ESRD, where RF is nearly universal

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10.1016/j.jnutbio.2021.108911 84 HuangS.XingY.LiuY