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Phase 3: Optimize both (weeks 9-16) Increase AOD 9604 to 300-500mcg daily based on tolerance

GIP enhances insulin secretion in a glucose-dependent manner, meaning it boosts insulin release when blood sugar is elevated but does not push insulin levels dangerously low when blood sugar is normal

Some evidence suggests that B12 may help prevent or slow down the development of osteoporosis

AOD-9604 (Anti-Obesity Drug 9604) is a synthetic hexadecapeptide corresponding to residues 176-191 of human growth hormone, with a tyrosine substitution at the N-terminus and an intramolecular disulfide bridge (Cys7-Cys14)

It stimulates lipolysis (breakdown of stored fats) and inhibits lipogenesis (formation of new fat), primarily via activation of -adrenergic and AMP-activated protein kinase (AMPK) pathways