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Iron deficiency induced hepatic inflammation and activated TLR4/NF-B pathway in suckling piglets RNA-seq profiling of liver tissue from suckling piglets demonstrated a significant enrichment of immune-related terms (biological processes GO and KEGG pathways) in the ID group, such as activation of immune responses, regulation of immune responses, cytokine production, chemokine signaling pathway, and Toll-like receptor (TLR) signaling pathway (Fig

[1] [2] The condition exists on a spectrum, ranging from simple steatosis (fat accumulation alone) to non-alcoholic steatohepatitis (NASH), where inflammation and liver cell damage occur alongside fat deposition

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