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3e), which are direct targets of BZR1, suggesting that SRDX also mediates the transcriptional activation function of BZR1

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Management of hypertension and renin-angiotensin-aldosterone system blockade in adults with diabetic kidney disease: Association of British clinical diabetologists and the renal association UK guideline update 2021

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In accounting for these findings, our own molecular modelling of the known sites for 4-HNE adduction within tubulin indicate that this form of modification is likely to cause both changes in the tertiary structure of the protein and importantly, alter the surface characteristics of the tubulin monomers